<International Circulation>: Translating the results from a clinical trial into clinical practice - can you tell us the general principles behind that? 《国际循环》:将临床试验的结果应用与医疗实践-您能跟我们讲讲其中的基本原则吗? Prof.Harrington: It’s a great question – how does one take clinical trial data and decide how to interpret that into clinical practice? There are a lot of steps along the way. The first one is to provide to the medical community the information from that clinical study in the peer-reviewed literature where the clinical community can see the scientific information in all of its detail in a very quantitative way. But the story doesn’t stop with the publication of the peer-reviewed literature. A lot of the dissemination then becomes people talking and giving presentations on the data; people talking to people in their local environment about how you might think about the data in the context of your own practice. Then there is the notion of how data gets into the practice guidelines such as those from the American Heart Association and the American College of Cardiology Guidelines from the European Society of Cardiology. That data then needs to be disseminated. Then the final point to mention is that a tremendous amount of effort is placed, both by the American Heart Association and the American College of Cardiology, on looking at the uptake of information using registries. That is another excellent way to understand how our therapy is being taken up into clinical practice. Harrington教授:这是问题很大-如何吸收临床试验的数据并将将其应用到临床实践中?在这方面还有很长的路要走。第一步就是给医疗界提供临床研究的信息,通过同阅读相关文献,医疗界可以批量详细了解到临床研究的科学信息。但是发表文献之后还有很多事要做。许多宣传变为人们就改资料进行讨论并且作相关汇报;人们从他们的角度谈论在你的实践过程中你是如何思考这些资料的。然后这种理念形成了,即理论资料是如何进入实践的,正如美国心脏病学会和制定美国心脏病学院指南的欧洲心脏病学会所说的那样。该资料还需要进一步宣传。最终目的是美国心脏病学会和美国心脏病学院付出巨大的努力,以观察注册研究的信息摄取。这是将治疗方法推广到临床实践的另一个很好的途径。
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